Renal Collecting Duct Cell‐specific mVps34 Deletion Decreases Nephron Number and Increases Nephron Size
نویسندگان
چکیده
منابع مشابه
Nephron number, hypertension, renal disease, and renal failure.
Wendy E. Hoy,* Michael D. Hughson, John F. Bertram, Rebecca Douglas-Denton, and Kerstin Amann *Centre for Chronic Disease, University of Queensland, Brisbane, Australia; University of Mississippi Medical Center, Jackson, Mississippi; Department of Anatomy and Cell Biology, School of Biomedical Sciences, Monash University, Victoria, Australia; and Department of Pathology, University of Erlangen-...
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Parathyroid hormone (PTH) transiently increases urinary excretion of the lysosomal enzyme, N-acetyl-beta-D-glucosaminidase, which is distributed mainly in proximal tubules. The response is reduced in pseudohypoparathyroidism (PHP) type I, which is characterized by target-organ resistance to PTH. Evidenced by normal calcium resorption, distal tubule sensitivity to PTH has been believed to be nor...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.705.11